Spontaneous self-assembly of RNA

In a new paper in the journal ChemBioChem, collaborator Niles Lehman and colleague report on the spontaneous covalent assembly of short RNA fragments, on average <40 nucleotides in length. They show that a dehydration-rehydration sequence is the most effective means to shift the self-assembly equilibrium from reactants to products.

T. S. Jayathilaka and N. Lehman. Spontaneous covalent self-assembly of the Azoarcus ribozyme from five fragments. ChemBioChem, 2017.

This entry was posted in Uncategorized. Bookmark the permalink.